Alcoholic Liver Disease Insights from Dr. Neerav Goyal

Alcoholic Liver Disease: Insights from Dr. Neerav Goyal

Alcoholic Liver Disease (ALD) is a significant cause of liver health problems and death around the world, usually causing problems after one drinks alcohol heavily for a long time. The disease has various types of liver damage, from simple steatosis (fatty liver) to liver cirrhosis and even liver cancer. ALD is preventable, but remains underdiagnosed and undertreated due to overlooking its slow progression and nonspecific signs. To understand ALD with greater detail, we would like to reach out to Dr. Neerav Goyal, one of the hepatology specialists, who provided useful information regarding pathophysiology, diagnosis, treatment, and even preventive measures concerning this disease.

Understanding Alcoholic Liver Disease: The Spectrum of Damage

ALD progresses over time, starting as a fatty liver and leading to advanced cirrhosis. Liver processing capacity for alcohol increases over time, but only to a certain point, after which the liver becomes overwhelmed. ALD can be described in components as follows:

Alcoholic Fatty Liver (Steatosis):

ALD’s first and most common stage is alcoholic fatty liver, which is characterised by fat accumulation in the liver cells. Most patients with steatosis are symptom-free, but the extra fat in the liver should alarm the patient because it means alcohol is beginning to impair liver metabolism. The positive news is, as Dr. Goyal points out, the liver can recover fully if alcohol intake ceases at this stage.

Alcoholic Hepatitis:

With further exposure to alcohol, liver inflammation and cell damage deepen, progressing toward alcoholic hepatitis. This condition is marked by jaundice, nausea, persistent abdominal pain, and fever, and in some cases, can progress to dangerously severe alcoholic hepatitis. Dr. Goyal says this condition is an emergency and needs to be treated right away. A timely treatment, on the other hand, can lead one to a healthier life.

Fibrosis and Cirrhosis:

Chronic drinking can lead to scarring of the tissue, known as fibrosis, which can advance to cirrhosis. The damage becoming permanent liver cirrhosis is the obliteration of the architecture and function of the organ. Complications include variceal bleeding, fluid buildup in the abdomen (ascites), and brain dysfunction due to liver failure (hepatic encephalopathy). “Dr. Goyal stated that while there is no turning back from cirrhosis, slowing down the liver’s deterioration is possible with early medical intervention.”

Hepatocellular Carcinoma (Liver Cancer):

Long-lasting cirrhosis, especially due to chronic alcohol consumption, sets the stage for liver cancer. Having liver cancer because of cirrhosis puts patients in a vulnerable situation. “Dr. Goyal emphasised the importance of continual monitoring for liver cancer in patients with cirrhosis, as the earlier it is diagnosed, the better the chances of surviving.”

The Pathophysiology: How Alcohol Damages the Liver

Dr. Goyal’s experience and research indicate that the harm to the liver from Alcoholic Liver Disease (ALD) is due to several reasons. It is mainly attributed to the breakdown of alcohol into acetaldehyde, due to alcohol dehydrogenase (ADH) and cytochrome P450 2E1 (CYP2E1). Acetaldehyde is such a substance that causes oxidative stress along with inflammation, and immune responses. All these lead to the liver cell damage.

Many other components worsen this process:

Oxidative Stress: The secondary damage to liver cells during oxidative stress is increased due to the free radicals caused by Alcohol metabolism.

Inflammatory response towards Acetaldehyde and its metabolites in the liver can start an immune response and release cytokines which invoke a fervent cascade inflicting additional damage to liver tissue.

Excessive inflammation is not alone, alcohol also disrupts the liver’s ability to break down and move fat which causes an increase of fat in liver cells.

As Dr. Goyal notes, steroid hormones have a considerable impact, too. Changes in the genes related to do with alcohol consumption, like ALDH2 (Aldehyde Dehydrogenase), greatly weaken someone’s resistance to Alcoholic liver Disease (ALD) because someone lacking ALDH2 is likely to suffer from severe injury to liver injury after consumption, while growing up in East Asian countries makes it even worse.

Main Danger Elements When Attempting to Diagnose Alcoholic Liver Disease

The primary suspect and tragic risk for ALD liver disease is severe drinking, but a variety of underlying factors could be contributing to simultaneously increasing ALD susceptibility:

Nationality is one of the most vital risk factors for suffering from ALD liver. As Dr. Goyal in-depth, changes in all metabolic uses and whether the immune system is involved in liver inflammation affect the rate of ALD cirrhosis.

Gender: Even taking into consideration a woman’s lower alcohol intake in comparison to males, they still tend to develop ALD at a greater rate. This is due to AFLD’s unique metabolism and hormonal composition, as well as body structure factors.

Comorbid Conditions: Existing causes like obesity, diabetes, and viral hepatitis worsen liver damage. These patients with double diseases are more susceptible due to the amplified impact these conditions tend to possess with alcohol intake. According to Dr. Goyal, these illnesses tend to enhance the already damaging impact alcohol has towards the liver.

Binge Drinking: The act of infrequently binge-drinking poses to be highly detrimental to the liver’s wellbeing. According to Dr. Goyal, binge drinking triggers acute alcoholic hepatitis, even in those who do not drink deeply.

Nutritional Deficiencies: In most cases, consuming alcohol for long periods without breaks leads to malnutrition. This does strenuous work to the liver since it greatly limits self-restoration capabilities. Dr. Goyal stresses full diet is essential in sustaining ALD and impersoning AFLD.

Diagnosing Alcoholic Liver Disease

As Dr. Goyal notes, to diagnose ALD, the history of alcohol intake along with ancillary methods of evaluation must be woven together.

Blood Tests: Liver function tests (LFTS) alongside some blood markers like gamma-glutamyl transferase (GGT) and mean corpuscular volume (MCV) can reflect some degree of liver damage. These do not cause alcoholic liver disorder; however, the diagnosis of ALD requires more answers. Investigations are usually incomplete.

Imaging: Fatty liver, liver fibrosis, and liver cirrhosis are some of the stages of the liver which can be evaluated using non-invasive imaging techniques like ultrasound, CT scan, or MRI. They play an important role in staging the disease.

Liver Biopsy: Liver biopsy is considered the gold standard of diagnosis ALD but it is seldom done because of its invasive nature. It is done while staging fibrosis of the liver in patients when there is some doubt regarding the diagnosis.

Management and Treatment of Alcoholic Liver Disease

Treating ALD is a complex process, as there are multiple strategies, but the common denominator remains preventing more damage and promoting repair to the liver. As presented by Dr. Goyal, these are some central principles of treatment:

Alcohol Abstinence: From the therapeutic perspective in ARL, the most effective measure is stopping alcohol. Dr. Goyal notes that even if the patient is in an advanced stage of the disease, stopping alcohol will control the damage, and liver function can improve.

Nutritional Support: Proper nutrition is essential for properly managing the health of ALD patients. Malnutrition is very common among patients with ALD. Having an increased dietary protein, while simultaneously lowering lipid intake, can enhance liver function and assist in recovery.

Medications: Corticosteroids and pentoxifylline are used in the treatment of severe alcoholic hepatitis to reduce inflammation. Patients who have cirrhosis also require treatment for complications of ascites, variceal bleeding, and hepatic encephalopathy.

Liver Transplantation: Liver transplantation is a therapy option for patients with end-stage liver disease (cirrhosis), but as Dr. Goyal points out, one of the requirements is having a history of abstaining from alcohol for a certain period.

Preventing Alcoholic Liver Disease

Dr. Goyal outlines focusing exclusively on prevention to manage ALD. He proposes public policy initiatives that aim to educate people on the dangers associated with alcohol misuse, as well as more proactive measures, such as early screening coupled with counselling for people prone to ALD.

Conclusion: Laying Out The Next Steps

ALD continues to be a public health concern for many people, and Dr. Goyal’s ALD lectures about the pathophysiology, diagnosis and treatment of the disease help accentuate the reality of proactive measures and the role of lifestyle modifications. The rising burden of ALD can be alleviated with timely diagnosis, increased healthcare access, lifted awareness levels, improved quality of care, and a shift towards responsible drinking practices.

ALD is complex in nature, and hepatologists from around the world highlight the importance of adopting a holistic strategy for prevention and management of the condition. This analysis advocates for tailored treatment strategies based on individual patient needs.

 

Yellowing eyes and skin – common symptom of jaundice

Jaundice: Understanding the Yellow Signal Your Body Sends

Jaundice. It’s one of those words you’ve probably heard from a doctor or seen in a movie. But do you know what it means? That yellowish tint in the eyes or skin isn’t just a random occurrence—it’s your body waving a big, yellow flag saying, “Hey! Something’s not right with the liver!”

In this article, we’re diving deep into jaundice in a way that’s easy to understand, even if you’ve never picked up a medical book in your life. We’ll also talk about what to do if things get serious, including how to find the Best Liver Transplant Surgeon in India—because when your liver talks, you need the right expert to listen.

1. What is Jaundice?

Jaundice isn’t an illness, but just a manifestation. Consider it an indication of a “check engine” light for the body, particularly your liver. If your eyes or skin change colour is due to the accumulation of a chemical known as bilirubin that your liver usually disposes of. When your liver isn’t functioning properly, the bilirubin levels start to build up, and the yellowing appears.

2. What Causes Jaundice?

Why does this alert turn yellow? There are a variety of reasons that can cause problems with the processing of bilirubin:

  • Liver ailments such as cirrhosis or hepatitis
  • Gallstones blocking the bile ducts
  • The infection that causes liver damage
  • Certain medications or alcohol damage
  • Gene-related disorders like Gilbert’s Syndrome

Simply put, everything that hinders or blocks the liver’s ability to perform its job could trigger jaundice.

3. Types of Jaundice

There are three major types of problems, based on the location where the issue first appears:

Pre-Hepatic Jaundice

It occurs before the liver gets involved. It’s typically due to ailments like sickle cell anaemia, in which red blood cells are destroyed too quickly.

Hepatic Jaundice

It is caused by issues in the liver that cause it, such as fatty liver disease, hepatitis, or cirrhosis.

Post-Hepatic Jaundice

Also referred to as Obstructive jaundice. Also known as obstructive, it happens following the liver is blocked, think of the liver ducts, because of cancerous gallstones.

4. Signs and Symptoms to Watch For

The most obvious indicator? The skin is yellowing or the eyes. But that’s not all. It is also possible to notice:

  • Urine with dark-colored hues
  • Pale-colored stool
  • Affective or weak
  • Nausea or vomiting
  • Abdominal discomfort or swelling
  • Itchy skin

If you notice any combination or combination of them, do not dismiss your liver’s attempt to speak to you!

5. Jaundice in Newborns

It’s normal for newborns to appear somewhat yellow following the birth. It’s because their livers still learning how to deal with the hormone bilirubin. Most times it will go away by itself. In some instances when bilirubin levels are too high the risk of a heart attack increases and require treatment such as the phototherapy (special treatment with light).

6. How Jaundice is Diagnosed

Doctors don’t simply go by appearances. Here’s how they make sense of things:

  • The blood tests are used to determine the liver’s function and levels of bilirubin
  • Ultrasounds or CT scans that look at the liver and bile ducts.
  • The biopsy of the Liver in certain severe instances

These tests allow you to pinpoint the exact cause and then identify the most effective treatment.

7. Is Jaundice Dangerous?

Sometimes, but not always. In cases of mild severity, especially when the cause is temporary, it’s possible to be cured by itself. If it’s related to an ongoing liver problem and is not treated, it could be dangerous if not addressed.

This is why obtaining the correct diagnosis in the early stages is vital.

8. How is Jaundice Treated?

The treatment is based on the cause:

  • Antibiotics to treat infections
  • Lifestyle modifications to treat fatty liver or alcohol-related issues
  • Stents or surgery to treat obstructions in the bile duct
  • Antiviral medication for Hepatitis
  • A liver transplant if the liver is damaged beyond repair

9. When is Liver Transplant Considered?

When the liver has reached an age where it is unable to no longer perform its function and the other treatment options have been unsuccessful, liver transplant is the only alternative. It’s a big decision, but it’s also life-saving.

Signs of warning that could cause a transplant:

  • Multiple jaundice episodes
  • Liver failure
  • Hepatocellular carcinoma (liver cancer)
  • Cirrhosis severe

This is why choosing the best liver transplant surgeon in India is essential, since experience can make all the difference.

10. Best Liver Transplant Surgeon in India

India is recognised globally for its highly skilled surgeons and sophisticated liver transplantation programs. The best Liver Transplant Surgeon in India will provide:

  • High rate of success during transplant surgeries
  • Modern medical facilities that have liver ICUS
  • Affordable treatment options
  • Post-transplant assistance and rehabilitation

No matter if you’re living in Delhi, Chennai, Hyderabad, or Mumbai, make sure you verify credentials, testimonials from patients and the hospital’s infrastructure before making a decision.

11. Preventing Jaundice – Can It Be Avoided?

In many cases, yes. Here’s how to keep your liver well:

  • Avoid excessive alcohol
  • Be vaccinated against Hepatitis A and B
  • Keep a healthy weight and diet. lose weight
  • Take your medication with care.
  • Do not share needles or personal objects

Consider your liver as the body’s filter. Take care of it!

12. Jaundice Diet – What to Eat and What to Avoid

Food can be your most effective remedy. Here’s how:

Eat More Of:

  • Fresh fruits (papaya, apples, berries)
  • Leafy greens
  • Turmeric (anti-inflammatory)
  • Plenty of water

Avoid:

  • Foods that are oily, fried or processed
  • Alcohol
  • Sugary drinks
  • Salt that is too much

Keep in mind that the food you put in your mouth can affect your liver’s function directly.

13. Myths and Facts About Jaundice

Let’s dispel a few of the most common myths:

Myth: Jaundice is transmitted from one person to the next.

Fact: It’s not contagious–unless it’s caused by an infectious disease such as Hepatitis.

The myth: You should avoid the use of turmeric in jaundice.

Fact: Turmeric has liver-protecting properties!

The myth: Only alcoholics get jaundice.

Fact: Even non-drinkers can be suffering from liver problems because of an unhealthy liver, infections or genetic issues.

14. Emotional and Mental Health During Liver Illness

A chronic liver problem can take a toll not only on your body, but also on your mental and emotional well-being. Stress, anxiety, and stress are all common. This is why counselling, support groups, and conversations with loved ones could be as effective as medications.

15. Final Thoughts – Listen to Your Liver

Jaundice isn’t just about the colour of your eyes. It’s a sign that your liver could be getting a little shaky. The faster you act on the signs, the greater your chance of avoiding damage that could last for a long time. If the problem becomes severe, do not be afraid to seek out the most reputable liver transplant surgeon in India. Because your liver deserves nothing less than the very highest quality.

Frequently Asked Questions (FAQS)

1. Does jaundice disappear by itself? Yes, mild jaundice will disappear in its own time, especially when it is caused by temporary problems such as minor infections or medication adverse effects.

2. What is the time frame to heal from jaundice? It’s dependent on the cause. For instance, viral jaundice could last a few weeks, while chronic liver problems can last for months or require a lifetime of treatment.

3. Is a liver transplant the only option for severe jaundice, but not always. A transplant is only required in cases of liver failure, and all other treatment options have not worked.

4. How can I locate the most effective liver transplant specialist in India? Do you look for surgeons who are board-certified in the top hospitals, who have excellent customer reviews with high success rates and excellent aftercare service?.

5. Does jaundice in adults differ from that of newborns? The answer is yes, newborn jaundice is generally harmless and only temporary, but adult jaundice typically suggests an underlying liver problem.

 

 

 

Dr. Neerav Goyal – Leading Liver Transplant Surgeon at Apollo Hospital, India

Minimally Invasive Donor Hepatectomy: A Safer Path to Saving Lives

By the Liver Transplant and HPB Surgery Unit, Indraprastha Apollo Hospital

At the Liver Transplant and HPB Surgery Unit at Indraprastha Apollo Hospital, we believe that saving a life should not compromise another. That’s why we’ve embraced the future of living donor liver surgery—Minimally Invasive Donor Hepatectomy (MIDH).

💡 What Is Minimally Invasive Donor Hepatectomy?

It’s a highly advanced surgical technique where a portion of a healthy person’s liver is removed using small incisions, laparoscopic tools, or robotic assistance. Unlike traditional open surgery, this approach focuses on reducing pain, scarring, and recovery time for the donor—who is usually a family member or loved one.

💪 Why It Matters to Us—and You

We’ve seen firsthand the generosity of our donors. They step forward selflessly, and we’re committed to honoring that act by making the process as safe and smooth as possible.

With MIDH, our donors experience:

  • ✅ Less postoperative pain
  • ✅ Smaller, almost invisible scars
    • ✅ Faster recovery and earlier return to normal life
    • ✅ Greater confidence in stepping forward
  • 🛠️ Our Approach at Apollo

    Our unit offers both:

    • Laparoscopic Donor Hepatectomy – Ideal for pediatric or left lobe donations.
    • Robotic Donor Hepatectomy – Preferred for right lobe donation, offering unmatched precision and surgeon control.

    Using the da Vinci robotic system, our experienced team performs complex liver surgeries with a focus on donor safety, exceptional outcomes, and rapid recovery.

    👤 Who Can Be a Candidate?

    Each potential donor undergoes a detailed assessment to ensure:

    • Safe liver anatomy
    • Good overall health
    • Appropriate lobe selection (left, right, or left lateral)
    • Full understanding of the process and risks
      • ✅ Faster recovery and earlier return to normal life
      • ✅ Greater confidence in stepping forward
    • 🇮🇳 A Leading Program in India

      Our center at Indraprastha Apollo Hospital is among the few in India offering robotic donor hepatectomy with outcomes that match global benchmarks. We’ve successfully performed numerous minimally invasive liver donations, with excellent recovery and feedback from donors.

      ❤️ A Donor’s Gift Shouldn’t Leave a Mark

      Minimally invasive liver donation is another way we honor our donors—with better safety, recovery, and dignity.

      If you or a loved one is considering living liver donation, we invite you to consult with our expert team  

    • By the Liver Transplant and HPB Surgery Unit, Indraprastha Apollo Hospital  
      • Looking for the best liver transplant surgeon in India? Meet Dr. Neerav Goyal at Apollo Hospital—renowned for world-class expertise, advanced minimally invasive techniques, and compassionate patient care. Book a consultation today 8527516541
Worried About Fatty Liver? Here’s What You Need to Know

Worried About Fatty Liver? Here’s What You Need to Know

Initially, the term fatty liver may feel foreign to some. Many people are facing the condition, even if they don’t know it. The moment you hear about NAFLD or fatty liver from either your doctor or healthcare provider, the level of concern rises. Such moments can be fortunate when one possesses the right set of information that can help alter one’s lifestyle, heal the liver, and add life.

Every organ of the body comes with a certain level of responsibility. When it comes to a ‘detoxifying plant’ or the icor of purification in the body, there lies the liver. Like any other organ, your liver performs its own set of tasks — filtering toxins, energizing the body, healing and even aiding digestion, among other essential duties. Imagine a case where everything you enjoy starts stopping the machine. The fatty liver congestion can impact the health of several parts, and ultimately, it is not ideal and is where help is needed.

Worried about fatty liver? Learn about NAFLD, ALD, symptoms, causes, diagnosis, and how to reverse fatty liver naturally. Discover prevention tips, treatment options, and the best liver transplant surgeons in India.

What Is Fatty Liver Disease?

When excess fat builds up in the liver, one is now facing fatty liver disease. Relatively, a small quantity of fat does not harm; however, the imbalance can impair crucial liver functions. In other words, it’s akin to operating a car with a blocked oil filter. All may seem well at first, but maintenance and repairs incur heavy losses.

There are two forms: one linked to alcohol (ALD) and the other non-alcoholic (NAFLD). Both have different sets of causes and treatment options, though they can be equally damaging.

Types of Fatty Liver: NAFLD vs ALD

NAFLD (Non-Alcoholic Fatty Liver Disease) is particularly prevalent among individuals who do not consume alcohol, but have obesity, diabetes, and high cholesterol.

Alcohol-Related Liver Disease (ALD) is a direct result of heavy drinking or alcoholism. The two can lead to inflammation of the liver, scarring (fibrosis), and even cirrhosis.

What Causes Fatty Liver?

There are several reasons why fat accumulates in the liver:

Unhealthy diet- Intake of sugary, processed, and deep-fried foods significantly increases.

Obesity- Especially visceral fat.

Diabetes- Heightened insulin resistance significantly contributes.

High cholesterol or triglycerides.

Rapid weight loss.

Genetic Factors.

Some medications.

It is rarely one contributing factor, as the reasons tend to be multi-faceted in terms of lifestyle behaviors and genetic factors.

 Signs and Symptoms You Should Not Disregard

Many people suffering from fatty liver do not notice symptoms in the beginning. That, right there, is what makes it dangerous. But as it progresses, look out for:

Lower energy levels
Discomfort in the upper right portion of the stomach
Unexplained weight loss
Abdominal swelling
Skin or eyes turning yellow (jaundice)

Feeling ‘off’ for a few days? It makes sense to consider a visit to the clinic.

What Is the Process of Diagnosing Fatty Liver?

Your practitioner may start with blood tests where elevated liver enzymes are shown. If those numbers are high, they will likely proceed with:

Ultrasound or CT scan
Fibroscan (To evaluate the stiffness of the liver)
Liver Biopsy (For more serious cases)

Timely diagnosis is crucial to avoid complications.

Is There a Chance Fatty Liver Can Be Reversed?

This is the deeply hopeful part; in most cases, fatty liver tends to be reversible, especially in the early stages. The liver is unique in a way that it can heal itself. Think of it like how a lizard regrows its tail. But, you must create the right conditions for it to do so.

Healthy Lifestyle Changes That Help

This is not only recommendations, but life-changing suggestions as well:

Lose weight achieved through gradual methods (say no to crash dieting!)
Regular exercise (even a simple 30-minute walk does the job!)
Avoiding alcohol of any form (especially with any liver problems)
Controlling blood sugar and diabetes
Drinking adequate water

Small changes have the potential to do a lot.

Foods That Heal (and Harm) Your Liver
Best foods for your liver:
Spinach & Kale (leafy greens)
Whole grain oats
Salmon (a type of fatty fish)
Walnuts (all nuts but mostly these)
Olive oil
Green tea
Fried foods
White bread, pasta, Sugary drinks, and red meat in excess
Alcohol
Colorful, well-balanced meals aid your liver.

Fatty Liver Gets Serious

Hiding until turning into NASH, fibrosis, or Cirrhosis is where fatty liver tends to silently go. Those are warning indicators of the liver being damaged or inflamed.
Cirrhosis and liver failure, along with liver cancer, er are where fatty liver disease can once left untreated. Action right on it early is crucial.
10 What Is Cirrhosis and Why It Matters

A permanently damaged scarred Liver is known as Cirrhosis. Losing the ability to function will result in the end stage needing continuous treatment, regular checks, and, in the worst case, liver replacement.

It is the body’s method of signaling that, “I’ve experienced enough.”

Role of Liver Transplants in Severe Cases

In some instances, when the liver has sustained so much damage that it cannot function even with lifestyle changes and medications, a liver transplant may be the only solution.

For many, it is a daunting prospect, but it can be a life-altering opportunity. When comparing liver transplants, India boasts of its great saviors and facilitiesthe of its physicians. India is also known for its skilled surgeons as well.

The Best Liver Transplant Surgeon in India

In the case that you or someone close to you undergoes a transplant surgery, select the Best Liver Transplant Surgeon in India. They are bound to make an incredible difference.

Consider The Following:

Experience: A minimum of several years of performing transplants.

Specialization: Exclusive to liver and gastrointestinal surgery.

Hospital affiliation: Owning an up-to-date hospital.

Hearing patient reviews: Genuine stories, not fabricated. Indias best.

With these guidelines, Indoaborad can provide you with a transit to India and arrange a meeting with world-renowned doctors, who provide flawless assistance even at favorable rates.

 Preventing Fatty Liver — Start Early

Start Prevention before the symptoms arrive.

A primary step is scheduling regular medical checkups
Attendance in ensuring physical activities is a must
Having appropriate measures concerning sugar is essential
Substituting sodas with water is ideal. Your liver will repay you in time.14 — Mental Health And Liver Disease

Health problems can be overwhelming to deal with, but the psychological impacts should not be neglected. Anxiety and depression are quite common alongside persistent health problems, one of which can be fatty liver disease.

Talk to someone. You can build a coping strategy and stay motivated through therapy, counseling, or support groups.

Your Next Steps — Take Action Now

So what happens next?

Have a conversation with your healthcare provider.

If you’re at risk, get screened.

Implement small changes to your everyday routine.

Instruct your family members.

Look into treatment options early.

Do not put off seeking help until the situation worsens because your liver is a silent workhorse, and you should start being its hero now

Dr. Neerav Goyal as a liver transplant specialist:
To seek a consultation with the best liver transplant doctor in New Delhi, India:
Call us at 8527516541 | Email at [email protected]

FAQs

1 — Is fatty liver disease life-threatening?

Not in every case. During the initial stages, it’s usually reversible, but it can progress into serious conditions, including cirrhosis and liver failure, if neglected.

2 — Can I drink alcohol if I have fatty liver?

Drinking in moderation is still not recommended, as it can exacerbate damage to the liver.

3 — How long does it take to reverse fatty liver?

With the right lifestyle changes, you could notice improvements within a few months, and full reversal could take between six months to a year.

4. Which foods are harmful to those with fatty liver?

Steer clear of fried foods, sugary drinks, refined carbohydrates, and alcohol. Instead, focus on whole and unprocessed foods.

5. When is it appropriate for me to see a liver transplant surgeon?

It’s time to consider the Best Liver Transplant Surgeon in India if you have cirrhosis, end-stage liver disease, or liver cancer.

Liver transplant procedure for cancer types with survival

Liver Transplant: Treatment for Cancer Types & Survival

The procedure of liver transplantation (LT) is now an important method of treatment for certain kinds of cancers that affect the liver. When a liver is replaced by a healthy liver, it provides not only an opportunity to treat cancer but also gives patients the possibility of living longer and healthier lives. This article explores the significance of liver transplantation in the treatment of various types of cancer, as well as the rate of survival that comes with this procedure, as well as the major advancements made in this area.

In this article, we’ll explore how liver transplants serve as an effective treatment option for various cancer types, the role of the best liver transplant surgeons in India, and what patients can expect in terms of survival and recovery after the procedure.

Introduction to Liver Transplantation

The procedure of liver transplantation can be described as a procedure that involves the removal of the damaged or diseased liver and replacing it with a healthy, functioning liver from an organ donor. It’s a viable treatment for patients suffering from end-of-life liver disease as well as specific forms of cancers in the liver, particularly when the cancer is restricted to the liver. While a liver transplant isn’t appropriate for every cancer patient, however, it is typically looked at when other treatment options like chemotherapy or surgery are not viable anymore or if cancer has progressed. For many patients, a liver transplant may give the possibility of
an opportunity to live again. 

Kinds of Cancer Treatable with  Transplantation of the Liver

Liver transplants are most often utilized to treat two kinds of liver cancers, Hepatocellular
Cancer (HCC) and cholangiocarcinoma. Each one has its distinct characteristics as well as
treatment needs and results

Hepatocellular Carcinoma (HCC)
Hepatocellular cancer is by far the most prevalent type of liver cancer that usually occurs in
people with chronic liver disorders like cirrhosis. HCC is a form of cancer that develops when
the liver cells are cancerous due to damage sustained over time that is usually caused by
hepatitis C infections, alcohol dependence, or non-alcoholic fatty liver disease.
For patients suffering from advanced-stage HCC restricted to the liver, a liver transplant is a
great option for ensuring long-term survival. In certain cases, it’s the only treatment that is
curative, particularly when the tumor is not surgically removed because of the liver’s deficient
function.
Other Types of Cancers
Although HCC is by far the most commonly diagnosed liver cancer that is treated through
transplantation, other types of cancer like cholangiocarcinoma (bile duct cancer) and liver
metastases (cancer that has taken hold of the liver after having spread to other organs) can
be treated through the transplantation of a liver, but the incidence of these types is less.
Cholangiocarcinoma may be difficult to treat, however, liver transplants may provide patients
with a possibility of treatment if the cancer is located in the liver, and there is no evidence of
spreading. 

Indications for Liver Transplantation
The decision of whether to undergo the idea of a liver transplant to help with cancer
treatment depends on various aspects.
Cancer Stage and Liver Function
The stage of the cancer, as well as the general condition of the liver, are key factors. Inmanyn 
instances, a transplant is suggested when the tumour is not large and restricted to the liver
and when your liver is not functioning properly due to cancer or cirrhosis.
In patients with a severe stage, liver transplants may be le

How Does a Liver Transplant Work?
A liver transplant is an extensive procedure that involves taking out the damaged liver before
transferring the healthy liver from an organ donor. The procedure is carried out under general
anesthesia, and typically, the procedure takes up to an hour

Surgical Procedure
The surgeon cuts an incision through the abdomen to allow access to the liver. A damaged or
destroyed liver will be removed, and the donor’s liver is then carefully transferred into the
body of the patient. The bile ducts and blood vessels are connected so that the liver can
perform as it should.
Donor Liver Types
Donor livers can be derived from deceased donors or living donors

Living Donor Vs. deceased Donor
In a live-donor transplant, the donor is healthy and donates part of their liver. Because the
liver can regenerate, both the donor’s and the recipient’s livers can likely grow with time.
Donors who have died will receive organs from deceased donors, and the organs must be
sized to match the body of the recipient as well as blood types.

Success Rates of Liver Transplants

for Cancer
The rate of success for liver transplantation for cancer is dependent on many factors, which
include the kind of cancer, the stage of the disease, as well as the general health of the patient.
Statistical Data on Survival Rates
The general rule is that the survival rate for transplants to the liver can be very high.
According to the latest statistics, the five-year survival rate of recipients of liver transplants
is between 70 and 80 per cent, however, this can vary depending on the patient’s medical
condition and the kind that is being received.

Factors Affecting Survival
Many factors affect the chance of survival, including patients’ age and general health as well
as to what degree the patient’s liver is compatible with the donor’s liver, and whether the cancer
will recur following transplantation. For instance, younger patients who are
diagnosed with hepatocellular cancer in early stages are more likely to survive as compared
to patients with higher-grade cancer

Post-Transplant Care and Management

Following a liver transplant, the patient’s recovery requires a long and extensive treatment
regimen.
Lifelong Care for Liver Transplant Recipients
After this procedure, the patients are required to be on immunosuppressive medication to
stop the body’s rejection of the newly created liver. These medicines must be taken for the
rest of their lives.
Lifestyle modifications, like eating a balanced diet and consistent exercising, are crucial to
keeping the health of the new liver. Regular follow-up visits with the medical team will make
sure your transplant is working properly and that there are no indications of cancer
recurrence.
Risks and Complications
Like any major operation, liver transplantation comes with risks. Possible complications
could include rejection, infection of the donor’s liver and the recurrence or recurrence. Close
monitoring of the transplant is vital in identifying any problems in the early stages.

Survival Rates and Prognosis
The outlook for patients who have received a liver transplant and have cancer is generally
good, particularly when they meet the requirements for a successful transplant. Cancer
recurrence is a possibility; however, advancements in medical treatment, such as
post-transplant surveillance, have led to improved survival rates over the long term.
Advances in Liver Transplantation
Technology
In recent times, there have been major improvements in technology for liver transplantation, 
which include improved immunosuppressive medications and better methods for preserving
organs. These advancements continue to improve the safety and effectiveness of liver
transplants.

What You Need to Know Before a
Liver Transplant
Anyone considering a liver transplant must be aware of the conditions for being put on the list
for transplants that include medical examinations, tests and the necessity to keep a healthy
lifestyle.

FAQs

Q1 Who is eligible for liver transplants for cancer?
A1 The eligibility criteria are based on the kind of cancer it is, its stage, liver function and
general health. A1: The Milan Criteria are commonly used to determine whether a patient is
eligible.

Q2 How long will it take to heal from an organ transplant?
A2 Recovery may take a few weeks, the initial couple of weeks of recovery being the most
crucial. Recovery and returning to normal activities could take as long as 1 year.

Q3 What are the dangers of undergoing a liver transplant?
A3 The risks include rejection of the organ as well as bleeding, infection and an increase in
cancer recurrence. Monitoring and treatment with care can help manage these risks.

Q4 What is the survival rate of liver transplant recipients?
A4 Five-year rate of survival of recipients of liver transplants is between 70-80%, based on
factors such as health, age and the stage of cancer.

Q5 What is the possibility of a liver transplant to help treat liver cancer?
A5 In certain instances, the liver transplant can treat liver cancer, particularly in cases where
the cancer is located within the liver and has not progressed.

Q6. What can I expect following the liver transplant?
A6 The post-transplant treatment includes the use of immunosuppressive drugs along with
lifestyle changes and regular checks to check the function of the liver and identify indications
of cancer or recurrence.

Conclusion
Liver transplantation can be a lifesaving procedure for a lot of cancer patients, providing an
opportunity to live and an improved quality. Although the procedure and recovery
process require meticulous planning and monitoring, the results are significant. As
technology advances, the prospects for patients who undergo liver transplantation remain
positive with higher success rates and better handling of any complications.

Dr. Neerav Goyal is the Best liver transplant surgeon in India, specializing in complex liver surgeries. With years of experience, he is dedicated to providing the best care for his patients. Contact him today to explore the best treatment options for your liver health.

Advanced Liver Transplant and HPB Surgery Unit at Indraprastha Apollo Hospital, providing expert care for liver diseases

Living with Hepatitis B or C: How We Manage and Treat Chronic Liver Disease

By the Liver Transplant and HPB Surgery Unit, Indraprastha Apollo Hospital

At the Liver Transplant and HPB Surgery Unit at Indraprastha Apollo Hospital, we meet hundreds of patients each year silently battling Hepatitis B and C—the two leading causes of chronic liver disease and cirrhosis in India and across the world.

The good news? With timely diagnosis and the right treatment, most people can live full, healthy lives—and even avoid liver failure.

🦠 The Long Shadow of Hepatitis B & C

These viruses infect the liver and, over the years, lead to:

  • Liver inflammation
  • Fibrosis (scarring)
  • Cirrhosis (end-stage liver damage)
  • Liver cancer in some cases

In many patients, there are no symptoms for years until liver damage is already advanced.

📍 Real Stories from Our Unit

A 42-year-old man came to us with mild fatigue and bloating. Routine blood work revealed he had chronic Hepatitis C—something he didn’t even know he was carrying for over a decade. Within 3 months of starting antiviral therapy, his viral load was undetectable and his energy returned.

In another case, a young woman with Hepatitis B was initially told she would eventually need a transplant. With the proper medication and monitoring, her liver function has stabilized—and she continues to work, travel, and raise her children.

🔍 How We Diagnose

  • Liver function tests (LFTs)
  • Viral markers (HBsAg, Anti-HCV, HBeAg, HBV DNA, HCV RNA)
  • FibroScan (non-invasive liver stiffness assessment)
  • Ultrasound or MRI to check for fibrosis, nodules, or cancer
  • Occasionally, a liver biopsy

💊 Treatment Options We Offer

For Hepatitis B:

  • Long-term antiviral medications (e.g., TenofovirEntecavir) to suppress the virus
  • Regular monitoring for liver function and liver cancer.
  • For Hepatitis C:
    • Curable in most patients with oral Direct-Acting Antivirals (DAAs) for 8–12 weeks
    • 95–98% success rate—even in patients with cirrhosis

    🧠 What We Tell Every Patient

    • You are not alone. Millions are living with hepatitis and doing well.
    • Get regular follow-up. Liver cancer can develop silently—we screen every 6 months.
    • Tell your family. Early testing and vaccination (for Hep B) can prevent spread.
    • If needed, we are ready for transplant. For those with advanced liver damage, we offer world-class living donor and deceased donor liver transplantation.

    🌿 Your Liver Can Heal—Let’s Help It

    At our unit, our approach is never one-size-fits-all. Whether you’re newly diagnosed or have lived with hepatitis for years, we offer:

    • Personalized treatment plans
    • Supportive diet and lifestyle guidance
    • Liver transplant evaluation if needed
    • Compassionate care from a dedicated team
    • Consult Dr. Neerav Goyal, one of the best liver transplant surgeons in India, offering expert care and advanced treatments

14 Signs of Liver Damage you should never ignore

The liver is one of the most vital organs in the body, and its health is crucial to overall well-being. When the liver begins to fail or show signs of damage, it can often go unnoticed until it’s too late. That’s why it’s important to be aware of the signs of liver damage and take action as soon as possible. This article will explore the 14 signs of liver damage you should never ignore, along with common causes, diagnostic methods, prevention tips, and the best course of action to take if you suspect liver damage.

Introduction to Liver Damage

Liver damage can occur for a variety of reasons and may not always manifest symptoms immediately. The liver is capable of regenerating itself to some extent, but if the damage continues or becomes severe, it can lead to conditions such as cirrhosis or liver cancer. In many cases, liver damage goes unnoticed because the early symptoms can be subtle. Understanding the warning signs of liver damage is essential for early intervention and treatment.

What is Liver Damage?

Liver damage refers to the harm or injury caused to the liver tissue, disrupting its ability to function properly. The liver plays a key role in detoxifying harmful substances from the blood, producing bile, and regulating metabolic functions. When the liver is damaged, these processes can be affected, leading to serious health problems. Some common forms of liver damage include fatty liver disease, hepatitis, cirrhosis, and liver fibrosis.

Common Causes of Liver Damage Several factors can lead to liver damage. It’s important to identify the root cause of liver injury to develop an effective treatment plan.

Alcohol Abuse: Excessive drinking over an extended period can lead to alcohol-related liver disease. The liver processes alcohol, but consuming too much can overwhelm its capacity, leading to inflammation, fatty liver disease, and cirrhosis.

Hepatitis Infections: Hepatitis is a viral infection that causes inflammation in the liver. Hepatitis B and C are the most common forms that can lead to chronic liver damage, potentially causing cirrhosis or liver cancer.

Fatty Liver Disease: Non-alcoholic fatty liver disease (NAFLD) is a condition where fat accumulates in the liver, even in those who do not consume alcohol. It is often linked to obesity, diabetes, and high cholesterol.

Genetic Factors: Some people inherit liver diseases due to genetic conditions such as Wilson’s disease or hemochromatosis, both of which affect the liver’s ability to process certain substances.

14 Signs of Liver Damage You Should Never Ignore

If you’re concerned about your liver health, look for the following 14 warning signs of liver damage. Early detection is crucial for preventing serious complications.

Yellowing of the Skin and Eyes (Jaundice).

One of the most noticeable signs of liver damage is jaundice, where the skin and whites of the eyes turn yellow. This occurs because the liver is no longer able to process bilirubin, a byproduct of red blood cells.

Unexplained Fatigue.

If you’re constantly feeling tired, weak, or lacking energy, it could be a sign that your liver is struggling to perform its detoxification tasks.

Abdominal Pain and Swelling.

Pain or tenderness in the upper right side of the abdomen may indicate liver inflammation. Swelling can occur when the liver fails to properly filter toxins from the body.

Dark Urine and Pale Stool.

Changes in the color of your urine (dark or tea-colored) or stool (pale or clay-colored) can be signs of liver damage. These changes happen when the liver can’t process waste properly.

Nausea and Vomiting.

Frequent nausea or vomiting, especially when coupled with other symptoms of liver damage, is another warning sign.

Loss of Appetite.

A lack of appetite is common when the liver is damaged. If you feel full even after not eating much, it could be a sign of liver dysfunction.

Swollen Legs and Ankles.

Liver damage can cause fluid retention, leading to swelling in the lower extremities, such as your legs, feet, and ankles.

Itchy Skin.

Persistent itchiness without an obvious cause could be linked to liver damage, as the buildup of bile salts can affect the skin.

Easy Bruising or Bleeding.

If you notice that you bruise easily or bleed excessively, it could be due to the liver’s reduced ability to produce clotting factors.

Confusion or Difficulty Thinking.

Liver damage can lead to a build-up of toxins in the brain, causing confusion, forgetfulness, or difficulty concentrating. This condition is known as hepatic encephalopathy.

Chronic Itchy Skin.

Itchy skin that doesn’t seem to go away may be another sign that your liver is not functioning properly.

Persistent Fever.

A persistent, low-grade fever along with other signs of liver damage could indicate liver inflammation or infection.

Changes in Skin Color or Texture.

If you notice dark spots, a yellow tint to your skin, or changes in the texture of your skin, these could be signs of liver problems.

Weight Loss.

Unexplained weight loss, particularly when combined with other symptoms like fatigue and loss of appetite, should not be ignored.

How Liver Damage Is Diagnosed.

Diagnosing liver damage involves several tests to assess liver function and determine the extent of the damage.

Blood Tests.

Blood tests such as liver function tests (LFTs) are commonly used to measure levels of enzymes, bilirubin, and proteins in the blood that can indicate liver dysfunction.

Imaging Tests.

Imaging tests, like ultrasound or CT scans, are often used to visualize liver abnormalities such as tumors, fatty deposits, or cirrhosis.

Biopsy.

In some cases, a liver biopsy is performed to obtain a sample of liver tissue for further examination.

How to Prevent Liver Damage.

Taking preventive measures is the best way to protect your liver from damage.

Maintain a Healthy Diet.

A balanced, low-fat diet rich in fruits, vegetables, and whole grains can help protect the liver from excess fat accumulation.

Limit Alcohol Intake.

Limiting alcohol consumption is crucial for liver health. If you choose to drink, it’s important to do so in moderation.

Avoid Harmful Medications.

Certain medications, when used improperly or in excessive amounts, can damage the liver. Always follow your doctor’s advice when taking prescription or over-the-counter drugs.

When to Seek Medical Help.

If you notice any of the signs mentioned above, it’s important to consult a healthcare provider as soon as possible. Early intervention can prevent liver damage from becoming more severe.

FAQs.

  1. How do I know if my liver is damaged? Common signs include jaundice, fatigue, abdominal pain, and changes in stool or urine color. A doctor can perform tests to confirm liver damage.
  2. Can liver damage be reversed? Some liver damage, particularly in the early stages, can be reversed with lifestyle changes and proper medical treatment.
  3. How long does it take for liver damage to occur? Liver damage can develop over many years, but some forms, like alcohol-induced liver damage, can progress more quickly.
  4. Is fatty liver disease reversible? Yes, in many cases, lifestyle changes such as weight loss, exercise, and a healthy diet can reverse fatty liver disease.
  5. What are the treatment options for liver damage? Treatment depends on the cause of the liver damage and may include medications, lifestyle changes, or in severe cases, a liver transplant.
  6. Can I drink alcohol if I have liver damage? It is recommended to avoid alcohol entirely if you have liver damage, as it can worsen the condition.

Conclusion.

Understanding the signs and symptoms of liver damage is crucial for early intervention and effective treatment. By recognizing these warning signs, you can take action to protect your liver and overall health. If you notice any of the symptoms mentioned in this article, seek medical advice promptly.

Cadaveric Liver Transplant: What you need to know

Cadaveric Liver Transplant: What you need to know
Liver transplants are frequently performed using cadavers, or deceased donors, as a source of organs. The deceased donors gave their prior permission to donate their organs. A donor’s liver is removed and maintained for transplantation, which needs to happen within 24 hours of the donor being deemed legally dead (brain dead). The cadaveric donor programme aims to achieve maximum organ by harvesting from potential donors, including the liver, and provide easy access to transplant services.

What is Cadaveric Liver Transplant?
The procedure known as “cadaver donor liver transplantation” or “deceased donor liver transplantation”  involves removing the liver from a brain-dead patient. A patient who is nearing the end of their liver failure receives a deceased donor liver transplant. Among the two liver transplantation techniques, cadaveric liver transplantation is one in which the deceased donor may have suffered a brain injury or been involved in an accident. What happens in a cadaveric liver transplant procedure?
 
A cerebral hemorrhage, head injury, or accident could possibly have affected the donor in a cadaveric liver transplant. Following the doctor’s official declaration of brain death, the organ is removed for donation with the family’s permission. A dead donor’s identity and the circumstances of their passing are kept private. The recipient’s waiting list position can always be discussed with the transplant coordinator and liver transplant surgeon.
 
A liver transplant from a deceased donor often requires four to fourteen hours of operation. The liver that was donated is transplanted after the injured liver is removed. 

Post-operative care for cadaveric liver transplant procedure
After surgery, recipients will be closely watched in the intensive care unit (ICU) to ensure that their bodies are not rejecting their organs. Depending on the patient’s condition, they may be sent to the general ward. Testing for liver rejection helps to determine the probability of rejection. Immunosuppressants are given to patients to avoid rejection. There is also nutritional guidance and physiotherapy provided. Individuals who undergo cadaveric liver transplant surgery usually recover successfully. Approximately 90% of patients receive a liver transplant and survive for a minimum of a year, and many go on to live considerably longer. The total success rate is between 85 and 90%. 

Final thoughts
The liver is an important organ in a body and is referred as human body’s powerhouse. It is the largest internal organ in the body which is situated beneath the diaphragm and above the stomach. Individuals who are suffering from end-stage liver illnesses or acute liver failure can benefit from cadaveric donor programme for liver transplants because these conditions may not be treated with therapy.

Best Liver Transplant Hospital in Delhi at Affordable Cost

In cases of severe liver illness, liver transplantation is a vital medical treatment that can save a patient’s life. The need for liver transplants is growing in India, especially in Delhi. At Liver Transplant International, one of the Best Liver Transplant Hospitals in Delhi, you can get  treatment at an affordable cost.
Why Liver Transplant?
When a person experiences either acute (sudden) or chronic liver failure, a liver transplant can save lives. Acute Liver Failure (ALF) occurs unexpectedly, and there could be several causes for it. Hepatitis A and E acute viral infections are the most common cause in India. End-stage liver disease, another name for chronic liver failure, develops more slowly over several months, years, or even decades. The most common cause of chronic liver failure is cirrhosis, a disease in which the liver’s cells gradually die and are replaced with scar tissue throughout.

Advantages of Getting Treatment at Liver Transplant International
Here are some of the advantages you can get at Liver Transplant International, one of the Best
Liver Transplant Hospital in Delhi:

● Affordable Cost: One of the main considerations impacting the decision-making process of liver transplants is cost. Liver Transplant International is a more affordable option for people seeking high-quality healthcare.● Skilled Professionals: Liver Transplant International has one of the best and most accomplished medical experts, Dr. Neerav Goal, his expertise in liver transplant is well-known in India.

● Shorter Wait Times: Patients’ wait times for transplants are considerably shorter in Liver Transplant International.

● Modern Infrastructure: We have state-of-the-art equipment and modern amenities, ensuring a superior standard of treatment.

Why choose us?
Liver Transplant International is among the Best Liver Transplant Hospital in Delhi. We take a holistic approach with our multidisciplinary team to treat a wide range of liver conditions. A specialized facility in Liver Transplant International offers complete care and treatments related to liver transplants. At the helm of our liver transplant program is a team of highly skilled and experienced doctors who have overseen and nurtured the program’s growth from its inception.

3 Most common liver conditions in children

Liver which is one of the most important human body part, does more than 500 functions in the body. It generates the waste-carrying bile, breaks down fats in the small intestine, filters the blood to remove toxins, and transforms extra glucose into glycogen for storage. It also improves
the immune system by fending off infections. There are several liver conditions that affect children, and here, the three most common liver conditions in children are discussed:

What is the liver’s function?
As the second largest organ in the body, the liver, which is located in the abdominal cavity, does multiple functions:
● Generates bile, a chemical that helps in food digestion
● Stores excess nutrients
● Helps clear the bloodstream of impurities
● Regulate the levels of cholesterol and blood sugar
● Makes proteins that allow blood to clot normally, transport oxygen, and support the immune system.

What is a liver disease?
Anything that affects or reduces the liver’s ability to function is referred to as liver disease. It can occur as a result of an illness, bad habits or behaviors, or exposure to specific chemicals. It can also be acquired through family traits. If the liver is damaged beyond curing through treatment,
then getting the Best Liver Transplant would be the wise option. Different pediatric liver conditions
Here are three important pediatric liver conditions:
1. Portal hypertension: The spleen and intestine supply blood to the liver through the portal vein. Portal hypertension is the medical term for conditions that involve high blood pressure in these blood arteries or liver-related blood flow resistance. New blood vessels, known as collaterals, grow as a result of this pressure. The collaterals join the intestine’s blood flow to the main circulation, bypassing the liver in the process. So, impurities that were meant to be filtered by the liver find their way into the bloodstream.

2. Autoimmune hepatitis: A child’s own body causes autoimmune hepatitis. An autoimmune disorder is an attack on the body by the immune system, which fights disease. Here, there is an attack on the liver cells. Over time, this affects the liver by causing inflammation. 

● Type 1: While it can start at any age, adolescence is the most common time for it to start (9 to 18 years old). Women and those with other autoimmune diseases like lupus, Crohn’s disease, or celiac disease are more likely to experience it.

● Type 2: In. It is more common in younger kids, particularly those with autoimmune disorders already.

3. Jaundice: Jaundice is caused by a rise in bilirubin in the body because of bile duct obstruction, liver cell abnormalities, or inflammation. It can occur as a result of the excessive destruction of a high concentration of red blood cells, which is common in neonates. The first and sometimes the only symptom of liver disease is jaundice.

Final thoughts Go to a reputable hospital as soon as possible if your child shows any of the symptoms or indicators of liver disease. Professionals there will correctly diagnose your child’s illness and start the best course of care. If there is a need for a liver transplant, then look for the Best Liver Transplant for a speedy recovery and rehabilitation.